Abstract:
Oral administration (0.2 ml./100g.b.w.) of six drugs for their anti-ovulatory and anti-implantation effects in female rats and four drugs for their anti-spermatogenic activities in malw mice were stuied. amongst the drugs screened on rats, juniperus Sabina was found to possess anti-ovulatory activity while azadirachta indica, Crocus sativus and Achyranthes apera were found to have anti- implantation activity. Viburnum opukus and Caulophyllum have showed both anti-ovulatory and anti-implantation activities. Mice treated with Lycopodium clavatum and Tumera diffusa were observed with distrupted permatogenesis. Mother tincture of sabal serrulate besides having anti - spermatogenesis effect, was found to affect epididymal sperm maturation. Anti- spermatogenic property has also been detected in Vitex angus castus to some extent. The results obtained in both female and male animals are encouraging and warrant further trials with the drugs on the larger number of subjects.
