Abstract:
Objective: To elicit the pathogenetic response of Gymnema sylvestre in homoeopathic
potencies on apparently healthy human volunteers. Methodology: Gymnema sylvestre
was proved by the Central Council for Research in Homoeopathy through double-blind
placebo-controlled method. The study was carried out at four centers. The drug was
proved in two potencies (6C and 30C) on 63 apparently healthy volunteers who were
selected after conducting pre-trial medical examination by the medical specialists and
routine laboratory investigations. In the first phase volunteers were given 56 doses
(04 doses per day for 14 days) of placebo. In the next two phases 56 doses (04 doses
per day for 14 days) of each potency or placebo were consumed. The symptoms
generated during the trial period were noted by the volunteers and elaborated by the
proving masters. The data obtained from all the four centers was compiled at provingcum-
data processing cell at CCRH headquarters after decoding. Results: Out of 37
provers who were on actual drug trial, 16 manifested symptoms. The drug was able to
produce symptoms in each potency in most of the parts of the body. Conclusion: The
pathogenetic responses elicited during the drug proving trial expand the scope of use
of the drug Gymnema sylvestre and will benefit the research scholars and clinicians.
The generated symptoms of the drug will carry more meaning when verified clinically.
