Abstract:
Background & objective: Uterine fibroids (UF) or leiomyomas are found in 25% to 35% women
of reproductive age. It is one of the most common indications for hysterectomy further leading to
complications. The present observational study on UF was undertaken to arrive at a group of useful
homoeopathic medicines for the treatment of the same.
Methods: A prospective observational study was conducted at Princess Durru Shehvar Children’s
and General Hospital, Hyderabad in coordination with its Extension Unit of Drug Standardization
Unit (Hyderabad) of Central Council for Research in Homoeopathy during September 2006 - August
2009. One hundred and thirty eight patients with UF were screened as per the pre-set criteria and 103
patients were enrolled. Homoeopathic Medicines were prescribed to the enrolled patients on the basis
of repertorization of the symptom totality. The improvement of the patients was assessed subjectively
through the clinical symptoms and objectively through USG pelvis.
Results: Out of 103 patients enrolled, follow up of 71 patients was completed as per protocol and
their data was analyzed. In 12 patients, fibroids resolved completely. There was statistically significant
reduction in some of the symptoms/signs as well as in size of fibroid(s) (p= <0.05). Calcarea carbonica
(n=16), Pulsatilla (n=14), Phosphorus (n=7), Lycopodium (n=5), Sulphur (n=3) and Kali carbonica
(n=2) were found to be most useful among the prescribed homoeopathic medicines.
Limitations: This was an observational study with no control arm, with the duration of follow up being
only 8 months.
Conclusion: This study has shown positive results in terms of reduction and resolution of UFs
with homoeopathic treatment. Further RCTs with long follow ups need be conducted for definite
conclusions.
