Abstract:
Objective: To elicit the pharmacodynamic response of the drug Pothos foetidus on healthy human
beings in non-toxic doses.
Methodology: Drug was proved through a double-blind method. The study was conducted at two
centres. The drug was proved in three potencies (6C, 30C and 200C) on 25 volunteers who were
selected and declared apparently healthy during their pre-trial medical examination by specialists
and through their routine pathological investigations. The volunteers consumed 56 doses (four
doses per day for fourteen days) of each potency (6C, 30C and 200C) in three stages for a varying
period. The symptoms generated during the trial period were noted by the volunteers and elaborated
and cross examined by the Proving Masters. The data obtained from both the centers was compiled
at proving-cum-data processing cell at CCRH headquarters after de-coding.
Observations: Out of the 18 provers who were on actual drug trial, 11 manifested symptoms. Drug
was able to produce symptoms in each potency more or less on every part of the body. Only a few
symptoms appeared in more than one prover. Some of the symptoms have been reproved which
are mentioned in the fragmentary provings published in different literatures.
Conclusion: Pharmacodynamic responses, elicited (new and reproved) during the proving trial
will add to the literature available on the drug and benefit the research scholars and clinicians.
This also needs verification through clinical trials.
