Abstract:
Objective of the study was to elicit the pathogenetic effects of Agave americana on
healthy human volunteers. The human pathogenetic trial was conducted at four Research
Institutes/Units of Central Council for Research in Homoeopathy (CCRH). It was a
randomized placebo controlled study, in which twenty eight volunteers participated, out
of which twenty were kept on drug and eight were on placebo. The drug has produced
certain skin and gastric symptoms similar to its known toxic effects, such as acute
contact dermatitis, gastric irritation. Besides, symptoms pertaining to other parts of the
body have also been brought out during the course of human pathogenetic trial.