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Adjunctive homeopathic treatment in patients with severe sepsis: a randomized, double-blind, placebo-controlled trial in an intensive care unit

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dc.contributor.author Frass, M
dc.contributor.author Linkesch, M
dc.contributor.author Banyai, S
dc.contributor.author Resch, G
dc.contributor.author Dielacher, C
dc.contributor.author Lobl, T
dc.contributor.author Endler, C
dc.contributor.author Haidvogl, M
dc.contributor.author Muchitsch, I
dc.contributor.author Schuster, E
dc.date.accessioned 2019-02-25T07:06:30Z
dc.date.available 2019-02-25T07:06:30Z
dc.date.issued 2005
dc.identifier.citation Homeopathy Vol. 94 en_US
dc.identifier.uri http://aohindia.in:8080/xmlui/handle/123456789/80
dc.description.abstract Background Mortality in patients with severe sepsis remains high despite the development of several therapeutic strategies. The aim of this randomized, double-blind, placebo-controlled trial was to evaluate whether homeopathy is able to influence long-term outcome in critically ill patients suffering from severe sepsis. Methods Seventy patients with severe sepsis received homeopathic treatment (n=35) or placebo (n=35). Five globules in a potency of 200c were given at 12 h interval during the stay at the intensive care unit. Survival after a 30 and 180 days was recorded. Results Three patients (2 homeopathy, 1 placebo) were excluded from the analyses because of incomplete data. All these patients survived. Baseline characteristics including age, sex, BMI, prior conditions, APACHE II score, signs of sepsis, number of organ failures, need for mechanical ventilation, need for vasopressors or veno-venous hemofiltration, and laboratory parameters were not significantly different between groups. On day 30, there was non-statistically significantly trend of survival in favour of homeopathy (verum 81.8%, placebo 67.7%, P=0.19). On day 180, survival was statistically significantly higher with verum homeopathy (75.8% vs 50.0%, P=0.043). No adverse effects were observed. Conclusions Our data suggest that homeopathic treatment may be an useful additional therapeutic measure with a long-term benefit for severely septic patients admitted to the intensive care unit. A constraint to wider application of this method is the limited number of trained homeopaths. en_US
dc.description.sponsorship CCRH en_US
dc.language.iso en en_US
dc.subject APACHE II; homeopathy; critically ill patients; intensive care unit; sepsis; survival; double-blind; randomized prospective; placebo-controlled study en_US
dc.title Adjunctive homeopathic treatment in patients with severe sepsis: a randomized, double-blind, placebo-controlled trial in an intensive care unit en_US
dc.type Article en_US


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