Abstract:
Objectives: To evaluate the usefulness of homoeopathic intervention in Schizophrenia,
in untreated cases and antipsychotic treatment resistant cases, to verify indications of
medicines, and to assess relapse, if any.
Materials and Methods: A prospective, non‑comparative, open‑label observational
study was carried out from October 2005–September 2010 by CCRH at Central
Research Institute (H), Kottayam, Kerala, India. Patients between 20 and 60 years of age,
presenting with symptoms of Schizophrenia were screened for inclusion and exclusion
criteria. The patients who were on antipsychotic drugs were allowed to continue the
same along with homoeopathic medicine, the dose of antipsychotics was monitored
by the Psychiatrist. The symptoms of each patient were repertorized, and medicine
was initially prescribed in 30C potency after consulting Materia Medica. Patients were
followed up for 12 months. Outcome of treatment was assessed with Brief Psychiatric
Rating Scales (BPRS). Analysis was done using Statistical Package for the Social
Sciences SPSS Version 20.0.
Results: Out of 188 enrolled patients, 17 cases did not complete the baseline
information. Total 171 patients were analysed as per modified Intention to Treat
Principle. Significant difference (P = 0.0001, P < 0.05) in the mean scores of BPRS,
using paired t test was observed at end of the study. Sulphur, Lycopodium, Natrum
muriaticum, Pulsatilla and Phosphorus were found to be the most useful medicines in
treating schizophrenic patients.
Conclusion: The study reflects the positive role of homoeopathic medicines in the management of patients
suffering from schizophrenia as measured by BPRS.
