Abstract:
Objective: To elicit the pathogenetic response of Caesalpinia bonducella in homoeopathic potencies
on healthy human volunteers.
Methodology: The drug Caesalpinia bonducella was proved by the Central Council for Research in
Homoeopathy (CCRH) through randomized, double-blind, placebo-controlled design. The proving was
conducted at three centres. The drug was proved in 6 & 30 centesimal potencies on 50 apparently
healthy volunteers, declared eligible after their pre-trial medical examinations by the medical specialists
and routine laboratory investigations. In first phase of proving, provers were given 56 doses of placebo
divided in 04 doses per day for 14 days. In next two phases, 56 doses of pre-selected potencies or
placebo as per the randomization were administered in divided doses same as in first phase. The
symptoms manifested during the trial period were noted down by the provers and elaborated by the
Proving Masters. The generated data of the drug from all three centres were compiled at provingcum-
data processing cell of CCRH headquarters after de-coding.
Observations: Out of 34 provers who were on actual drug trial, only 12 manifested symptoms. Drug
was able to manifest symptoms in both the potencies, in more or less every part of the body.
Conclusion: The pathogenetic response elicited during the proving trial, expands the scope of use of
the drug Caesalpinia bonducella and will benefit the research scholars and clinicians. The generated
symptoms of this drug will carry more value when verified clinically.
